Tomoka Hasegawa Selected Research

Juvenile osteoporosis

1/2020	Siglec-15-targeting therapy protects against glucocorticoid-induced osteoporosis of growing skeleton in juvenile rats.
11/2018	Siglec-15-targeting therapy increases bone mass in rats without impairing skeletal growth.

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Tomoka Hasegawa Research Topics

Disease

12	Osteoporosis 07/2022 - 09/2011
10	Bone Resorption 12/2021 - 09/2011
5	Neoplasms (Cancer) 01/2022 - 06/2019
2	Rheumatoid Arthritis 07/2022 - 12/2018
2	Squamous Cell Carcinoma of Head and Neck 01/2022 - 01/2021
2	Hyperphosphatemia 01/2022 - 01/2020
2	Carcinogenesis 01/2022 - 01/2021
2	Bone Diseases (Bone Disease) 01/2022 - 02/2011
2	Juvenile osteoporosis 01/2020 - 11/2018
2	Bone Fractures (Bone Fracture) 03/2019 - 01/2019
2	Rickets (Rachitis) 01/2018 - 10/2013
2	Obesity 12/2016 - 01/2016
1	Inflammation (Inflammations) 10/2021
1	Neoplasm Metastasis (Metastasis) 09/2021
1	Synovitis 08/2021
1	Infertility (Sterility) 01/2021
1	Pain (Aches) 12/2020
1	Osteolysis 10/2020
1	Periodontitis 06/2020
1	Osteosarcoma (Osteogenic Sarcoma) 07/2019
1	Nail-Patella Syndrome (Syndrome, Nail-Patella) 06/2019
1	Secondary Hyperparathyroidism 06/2019
1	Hypophosphatasia 01/2019
1	Stillbirth 01/2019
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2019
1	Dental Caries (Decay, Dental) 01/2019
1	Ankylosis 04/2018
1	Familial Hypophosphatemic Rickets (X-Linked Hypophosphatemia) 01/2018
1	Hypophosphatemic Rickets 01/2018
1	Granuloma 05/2017
1	Hypercalcemia (Milk Alkali Syndrome) 05/2017
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2017
1	Rib Fractures (Rib Fracture) 01/2016
1	Hypersensitivity (Allergy) 11/2015
1	Hypocalcemia 11/2015
1	Hypoparathyroidism 11/2015
1	Hypercalciuria 11/2015
1	Hyperglycemia 07/2015

Drug/Important Bio-Agent (IBA)

7	eldecalcitol (ED 71)IBA 09/2019 - 09/2011
6	Parathyroid Hormone (Parathormone)IBA 01/2022 - 11/2015
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 10/2014
5	Diphosphonates (Bisphosphonates)IBA 07/2022 - 09/2016
4	Cholecalciferol (Vitamin D3)FDA Link 09/2019 - 11/2015
4	Phosphates (Orthophosphate)IBA 04/2018 - 05/2015
3	GlucocorticoidsIBA 07/2022 - 01/2020
3	Biological ProductsIBA 01/2022 - 10/2013
3	Alendronate (Alendronate Sodium)FDA LinkGeneric 01/2022 - 09/2016
3	Pharmaceutical PreparationsIBA 09/2019 - 09/2011
3	Teriparatide (Parathar)FDA Link 03/2019 - 01/2019
3	Vitamin D FDA LinkGeneric 12/2016 - 09/2011
2	Fibroblast Growth Factor-23IBA 01/2022 - 01/2016
2	LipopolysaccharidesIBA 10/2021 - 08/2021
2	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 09/2021 - 01/2018
2	LectinsIBA 01/2020 - 11/2018
2	Neutralizing AntibodiesIBA 01/2020 - 11/2018
2	N-Acetylneuraminic Acid (Sialic Acid)IBA 01/2020 - 11/2018
2	Immunoglobulins (Immunoglobulin)IBA 01/2020 - 11/2018
2	OsteoprotegerinIBA 09/2019 - 02/2011
2	Alkaline PhosphataseIBA 01/2019 - 04/2018
2	CalciumIBA 04/2018 - 11/2015
2	IonsIBA 04/2018 - 05/2015
2	Interleukin-6 (Interleukin 6)IBA 01/2016 - 08/2014
1	Hormones (Hormone)IBA 01/2022
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2022
1	Tubulin ModulatorsIBA 01/2022
1	Phosphate Transport Proteins (Phosphate Transporter)IBA 01/2022
1	Histidine (L-Histidine)FDA Link 01/2022
1	InterferonsIBA 12/2021
1	cardiotrophin-like cytokineIBA 12/2021
1	Immunologic Factors (Immunomodulators)IBA 12/2021
1	calcium phosphateIBA 09/2021
1	ConnexinsIBA 01/2021
1	Connexin 43 (Connexin43)IBA 01/2021
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2021
1	Doxycycline (Periostat)FDA LinkGeneric 12/2020
1	IsotopesIBA 10/2020
1	CytokinesIBA 06/2020
1	LigandsIBA 09/2019
1	diallyl disulfide (diallyl disulphide)IBA 07/2019
1	Estrogens (Estrogen)FDA Link 01/2019
1	Streptozocin (Streptozotocin)FDA Link 01/2019
1	Anabolic AgentsIBA 01/2019
1	N- (4'- fluorobutyrophenone)- 4- (4- chlorophenyl)pyridinium (HPP(+))IBA 01/2019
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 12/2018
1	EnzymesIBA 04/2018
1	ectonucleotide pyrophosphatase phosphodiesterase 1IBA 04/2018
1	EndopeptidasesIBA 01/2018
1	1,25-dihydroxyvitamin DIBA 05/2017
1	25-hydroxyvitamin DIBA 05/2017
1	Messenger RNA (mRNA)IBA 01/2017
1	Leptin ReceptorsIBA 12/2016
1	Calcium-Sensing ReceptorsIBA 11/2015
1	JTT 305IBA 11/2015
1	Sorbitol (Yal)FDA Link 07/2015

Therapy/Procedure

4	Therapeutics 07/2022 - 11/2018
2	Aftercare (After-Treatment) 01/2022 - 05/2017
2	Ovariectomy (Oophorectomy) 01/2019 - 09/2011
1	Drug Therapy (Chemotherapy) 01/2022
1	Renal Dialysis (Hemodialysis) 06/2019
1	Parathyroidectomy 06/2019